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  • Title: Evaluation of serum beta 2-microglobulin in premalignant and malignant lesions of the oral cavity.
    Author: Anil S, Beena VT, Nair RG, Vijayakumar T.
    Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Endod; 1995 Jun; 79(6):750-2. PubMed ID: 7621034.
    Abstract:
    Serum beta-2-microglobulin was estimated in patients with oral leukoplakia, oral submucous fibrosis, and oral cancer. The results were compared with that of an equal number of age- and sex-matched healthy controls. A definite increase in the level of beta 2-microglobulin was observed in patients with oral submucous fibrosis and oral cancer. Though the level of beta 2-microglobulin was found to be high in oral leukoplakia, it was not statistically significant. Further studies will validate the role of beta 2-microglobulin estimation to predict the malignant potential of oral submucous fibrosis.
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