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  • Title: [Interleukin-1 production by exudate and bone marrow macrophages in experimental acute infectious peritonitis].
    Author: Dygaĭ AM, Klimenko NA, Bogdashin IV, Sherstoboev EIu, Gol'berg ED.
    Journal: Fiziol Zh (1994); 1994; 40(3-4):101-3. PubMed ID: 7621945.
    Abstract:
    The model of acute infectious peritonitis in mice has been used to show that inflammation is attended by a marked phasic increase in interleukin-1 (IL-1) production by macrophages of exudate and bone marrow. The increased IL-1 production by macrophages of exudate proceeds earlier than that by macrophages of the bone marrow. This indicates that activation of the bone marrow macrophages may be a result of the effect of OL-1 and other haemopoietic factors released by macrophages on the inflammatory focus.
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