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  • Title: Ectopic posterior pituitary tissue and paracentric inversion of the short arm of chromosome 1 in twins.
    Author: Siegel SF, Ahdab-Barmada M, Arslanian S, Foley TP.
    Journal: Eur J Endocrinol; 1995 Jul; 133(1):87-92. PubMed ID: 7627343.
    Abstract:
    Twin boys with hypopituitarism, hypoplasia of the anterior pituitary gland. ectopic posterior pituitary tissue and paracentric inversion of the short arm of chromosome 1 are described. The smooth appearance at the base of the median eminence and the absence of a pituitary stalk at autopsy in these boys implies that the hypopituitarism resulted from a developmental aberration. It remains to be determined if there is a casual relationship between the chromosome 1 anomaly and hypopituitarism.
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