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  • Title: Plasmapheresis and hemodialysis in the treatment of acute renal failure in multiple myeloma.
    Author: Kes P, Pecanić Z, Getaldić B.
    Journal: Acta Med Croatica; 1995; 49(1):39-42. PubMed ID: 7633177.
    Abstract:
    Two patients with multiple myeloma (IgA-kappa and IgG-lambda) and severe acute renal failure were treated by combined plasmapheresis and hemodialysis. In both patients renal function was restored to normal. The pathogenetic role of M-proteins and the possible mechanisms responsible for renal damage were discussed. While the addition of plasmapheresis has not been shown to extend survival, a reduction in the need for long-term dialysis appears to result from this intervention. It is concluded that the removal of M-proteins by plasmapheresis may be of therapeutic value in multiple myeloma patients.
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