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  • Title: Modulation of T-dependent cell-mediated immune responses by antigen-reactive cell opsonization and active suppression.
    Author: Bonavida B, Hutchinson IV.
    Journal: Transplant Proc; 1978 Mar; 10(1):31-5. PubMed ID: 76350.
    Abstract:
    We have studied both specific and non-specific suppression in allogeneic combinations. On the one hand, achievement of specific suppression may circumvent both HVGR and GVHR, while on the other, Cy-resistant suppressor cells may exacerbate the GVHR in bone marrow graft recipients. A greater understanding of both of these aspects of modulation of immune responsiveness will be important in clinical bone marrow transplantation.
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