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  • Title: The incidence of multifocal renal cell carcinoma in patients who are candidates for partial nephrectomy.
    Author: Whang M, O'Toole K, Bixon R, Brunetti J, Ikeguchi E, Olsson CA, Sawczuk TS, Benson MC.
    Journal: J Urol; 1995 Sep; 154(3):968-70; discussion 970-1. PubMed ID: 7637103.
    Abstract:
    PURPOSE: A prospective study was performed to determine the incidence of multifocal renal cell carcinoma in patients who are candidates for partial nephrectomy. MATERIALS AND METHODS: Preoperative imaging studies and surgical specimens in 44 patients suitable for partial nephrectomy but undergoing radical nephrectomy were prospectively reviewed. RESULTS: Of 44 renal cell cancers 11 (25%) demonstrated pathological multifocality, while 10 of 11 multifocal tumors (91%) occurred in the face of a primary tumor 5 cm. or smaller. Tumor multifocality was independent of the size of the primary renal tumor but occurred with a slightly higher frequency in tumors of stage T3A or greater even if the primary tumor was small. CONCLUSIONS: Partial nephrectomy in patients with unilateral renal cancer should be approached with caution and should not be performed simply because it is technically feasible.
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