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  • Title: Clinical and radiographic progression of fibrous dysplasia: cystic change or sarcoma? Description of a clinical case and review of the literature.
    Author: De Iure F, Campanacci L.
    Journal: Chir Organi Mov; 1995; 80(1):85-9. PubMed ID: 7641546.
    Abstract:
    The clinical and radiographic progression of fibrous dysplasia may be due to a cystic-hemorrhagic change, or to a sarcomatous transformation. The distinction between these two possibilities, which is essential to treatment, depend on the biopsy. A case of fibrous dysplasia in a female aged 18 years is described in which, 3 years after pathologic fracture consolidated with non-surgical treatment, clinical and radiographic progression occurred, enough to suspect malignant transformation. Histological diagnosis showed fibrous dysplasia with a cartilaginous component and cystic-hemorrhagic changes, and curettage-bone allografting resulted in healing of the lesion.
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