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  • Title: Visual acuity vs letter contrast sensitivity in retinitis pigmentosa.
    Author: Alexander KR, Derlacki DJ, Fishman GA.
    Journal: Vision Res; 1995 May; 35(10):1495-9. PubMed ID: 7645278.
    Abstract:
    This study examined the quantitative relationship between foveal visual acuity and contrast sensitivity for large-letter optotypes in a group of patients with retinitis pigmentosa (RP), in order to assess more completely the extent of foveal vision loss in this group of hereditary retinal dystrophies. High-contrast visual acuity and large-letter contrast sensitivity were measured with a computer-based testing system and with commercially available letter charts (Lighthouse Distance Visual Acuity Test; Pelli-Robson Contrast Sensitivity Chart). Findings from 20 patients with typical RP or Usher syndrome were compared with those from 15 age-similar control subjects with normal vision. On both the computer-based test and the chart tests, the patients with RP showed approximately equal reductions in visual acuity and large-letter contrast sensitivity. However, intersubject controls was greater for contrast sensitivity than for visual acuity on both test protocols. As a result, the patients with RP required a greater reduction in contrast sensitivity than in acuity to exceed the normal range, indicating that visual acuity was the more sensitive index of the loss of foveal visual function.
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