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  • Title: Long-term experience with the Ionescu-Shiley pericardial valve.
    Author: Masters RG, Walley VM, Pipe AL, Keon WJ.
    Journal: Ann Thorac Surg; 1995 Aug; 60(2 Suppl):S288-91. PubMed ID: 7646174.
    Abstract:
    To determine the long-term durability of the Ionescu-Shiley valve, we analyzed our experience with this valve at the University of Ottawa Heart Institute. To 1988, 780 patients have had aortic valve replacement (AVR = 528) or mitral valve replacement (MVR = 252). Of the aortic valves, 310 were standard profile and 218 were low profile. Of the mitral valves, 143 were standard profile and 109 were low profile. Actuarial survival at 10 years was as follows: AVR, 62% +/- 3%; MVR, 58% +/- 4%; p = 0.42. At 14 years, the results were AVR, 44% +/- 1% and MVR, 46% +/- 5%; p = 0.40. Reoperation was required in 197 patients. Structural failure was present in 85% of these valves, with leaflet tears alone in 69%, tears with calcification in 21%, and calcification alone in 10%. Leaflet tears occurred in 95% after AVR and in 78% after MVR (p = 0.006) and were seen in 95% of low-profile valves and 87% of standard-profile valves (p = 0.16). The actuarial freedom from reoperation at 10 years was: AVR, 58% +/- 3%; MVR, 62% +/- 5%; p = 0.49. At 13 years, these rates were 38% +/- 4% for AVR and 25% +/- 9% for MVR (p = 0.79). For AVR, the 10-year rate of freedom from reoperation was 57% +/- 4% for standard-profile valves and 57% +/- 8% for low-profile valves (p = 1.0). Similarly for MVR, the 10-year freedom from reoperation was 61% +/- 6% for standard-profile valves and 68% +/- 8% for low-profile valves.(ABSTRACT TRUNCATED AT 250 WORDS)
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