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  • Title: The effect of prednisone on the non-stimulated and the stimulated NBT test.
    Author: Wantzin GL.
    Journal: Biomedicine; 1975 Mar; 22(2):122-7. PubMed ID: 764890.
    Abstract:
    The non-stimulated and stimulated nitroblue tetrazolium (NBT) dye test was studied in five normal adults in sequence, viz. before and at intervals after prednisone was given as one large dose. A negative effect of prednisone on the NBT response was seen. This applied to both the non-stimulated and stimulated NBT test. For the latter five different toxins were used. At the same time a pronounced neutrophil granulocytosis was seen. The depression of the NBT test is present both in the percentage of NBT-stained neutrophils and when expressed in absolute counts of NBT-strained neutrophils.
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