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  • Title: [The centriolar complex of heterophasic homokaryons in the interphase and mitosis].
    Author: Onishchenko GE, Petrashchuk OM.
    Journal: Tsitologiia; 1994; 36(12):1192-9. PubMed ID: 7652932.
    Abstract:
    Two patterns of heterophasic centrioles occur in interphase polykaryons obtained by cell fusion: in the form of a united complex, or as groups scattered around the cytoplasm. By the start of mitosis, replication of centrioles is finished. There is no cellular center in polykaryons with mitotic asynchrony of nuclei. In these polykaryons pairs of centrioles are situated near each nucleus. In polykaryons with mitotic asynchrony the spindle forms asynchronously and mainly near condensed chromosomes. At metaphase, the spindles display a complicated multipolar organization. Associated by interpolar microtubules, the spindle poles are not always the nearest to each other and therefore kinetochore microtubules may be directed not to the nearest centrioles. Pairs of centrioles are located at the poles. The problem is discussed of the correlation between the centriole number and polykaryon ploidy, as well as of the role of multipolar mitosis in distribution of centrioles and chromosomes between daughter hybrid cells.
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