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  • Title: [Hairy cell leukemia and its treatment with 2-chlorodeoxyadenosine (2-CdA)].
    Author: Pawelski S.
    Journal: Acta Haematol Pol; 1995; 26(2):139-43. PubMed ID: 7653218.
    Abstract:
    In the last years a great progress was observed in the treatment of hairy cell leukaemia due to the introduction of interferon-alfa, pentostatin and above all -2-CdA. Through the programmed death - apoptosis of the hairy lymphocytes 2-CdA causes after 1-2 courses of treatment complete remissions in about 85% of previously treated as well as untreated patients. In the majority of them there are no symptoms of minimal residual disease and probability of their cure is significant.
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