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  • Title: The anticonvulsant hypersensitivity syndrome.
    Author: Handfield-Jones SE, Jenkins RE, Whittaker SJ, Besse CP, McGibbon DH.
    Journal: Br J Dermatol; 1993 Aug; 129(2):175-7. PubMed ID: 7654579.
    Abstract:
    Anticonvulsants can cause a characteristic hypersensitivity reaction. This multisystem reaction typically presents as fever, mucocutaneous eruptions, lymphadenopathy and hepatitis. There is cross-reactivity between different anticonvulsants, which complicates subsequent therapy. We report three cases to illustrate both the typical features, and less common complications, of this under-recognized and life-threatening syndrome.
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