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  • Title: Is prevention of preterm births in twin pregnancies possible? Analysis of the results of a prevention program in France (1989-1991).
    Author: Tafforeau J, Papiernik E, Richard A, Pons JC.
    Journal: Eur J Obstet Gynecol Reprod Biol; 1995 Apr; 59(2):169-74. PubMed ID: 7657011.
    Abstract:
    OBJECTIVES: A policy aimed at the prevention of early preterm births in twin pregnancies has been evaluated. The prevention program included: early diagnosis of twinning, information of the mothers about the risk of prematurity, attempts to restrain physical activity and early work leave prescription when indicated. STUDY DESIGN: Cohort study of all twin births in a given geographical area (Hauts-de-Seine district); 546 mothers with pregnancy duration of > or = 26 weeks were included; 1088 newborns were followed up to the 28th day of life. RESULTS: The recommended prevention program is largely used (88% of early diagnosis of twinning, 62% of the women informed and 73% of prescription for reduced physical activity). The very preterm (26-28 weeks) and early preterm (< or = 32 weeks) birth rates are low: 1.5 and 8.5%, respectively. The stillbirth rate is 11 per thousand and the neonatal mortality rate (0-27 days) is 10 per thousand live births, with a persistent difference between the first and the second twin. CONCLUSION: The present study demonstrates the open access and acceptability of the prevention policy; in addition, the perinatal outcomes are better than those of comparable published cohorts.
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