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  • Title: Bone marrow purging with dibutyl phthalate--experimental basis and a preliminary clinical application.
    Author: Wu C, Yang K, Pei X, Tang A, Wang F, Wang L.
    Journal: Leuk Res; 1995 Aug; 19(8):557-60. PubMed ID: 7658702.
    Abstract:
    It has been found recently that di-n-butyl phthalate (DBP) possesses a new pharmacological activity in the selective elimination of tumor cells from marrow. In combination with long-term liquid culture of marrow cells in vitro, DBP purged autologous bone marrow transplantation has first been applied to a case of acute myeloid leukemia at the first complete remission with successful reconstitution of hematopoiesis.
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