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Title: Control of Boophilus microplus populations in grazing cattle vaccinated with a recombinant Bm86 antigen preparation. Author: Rodríguez M, Penichet ML, Mouris AE, Labarta V, Luaces LL, Rubiera R, Cordovés C, Sánchez PA, Ramos E, Soto A. Journal: Vet Parasitol; 1995 Apr; 57(4):339-49. PubMed ID: 7660571. Abstract: Current methods for the control of cattle tick Boophilus microplus infestations are not effective and the parasite remains a serious problem for the cattle industry in tropical and subtropical areas. Recently, we developed a vaccine against B. microplus employing a recombinant Bm86 (rBm86) antigen preparation (Gavac, Heber Biotec) and it was shown to induce a protective response in vaccinated animals under controlled conditions. Here we show that, under field conditions in grazing cattle, the vaccine is able to control B. microplus populations. Two parasite-free farms were employed for the study. In the first farm, animals were vaccinated with the recombinant vaccine, while, in the second, animals received a saline injection in adjuvant. After immunization, animals were artificially infected and the infestation rate was recorded. Over the 33 weeks of the experiment, the infestation rate was lower in the vaccinated group compared with the control group. At the end of the experiment it was necessary to use chemicals in the control farm after serious losses in production and animals.[Abstract] [Full Text] [Related] [New Search]