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  • Title: The enzymatic cleavage of beta-carotene: still controversial.
    Author: Wolf G.
    Journal: Nutr Rev; 1995 May; 53(5):134-7. PubMed ID: 7666986.
    Abstract:
    The enzyme beta-carotene-15,15'-dioxygenase from guinea pig intestinal mucosa was found to cleave beta-carotene and produce 2 mol of retinal for 1 mol of beta-carotene. However, extensive evidence exists also for random (excentric) cleavage, resulting in retinoic acid and retinal, with a preponderance of apocarotenals formed as intermediates.
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