These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase.
    Author: Ui M, Okada T, Hazeki K, Hazeki O.
    Journal: Trends Biochem Sci; 1995 Aug; 20(8):303-7. PubMed ID: 7667888.
    Abstract:
    Wortmannin is a fungal metabolite that so far has been shown to act as a selective inhibitor of phosphoinositide 3-kinase. It can therefore be used to investigate the convergence between two major cellular signalling systems: those involving G-protein-coupled receptors and those involving receptor tyrosine kinases. Importantly, wortmannin can enter intact cells, making whole-cell studies of the above signalling pathways possible.
    [Abstract] [Full Text] [Related] [New Search]