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  • Title: Dysphoric response to neuroleptic treatment in schizophrenia and its prognostic significance.
    Author: Singh MM.
    Journal: Dis Nerv Syst; 1976 Apr; 37(4):191-6. PubMed ID: 767080.
    Abstract:
    Data on the subjective responses to neuroleptic treatment and their prognostic implications are reported from a multidimensional double-blind study of the pharmacotherapeutic process in schizophrenia. From these data it seems that the occurrence of a dysphoric response in the course of neuroleptic treatment is associated with a less favorable therapeutic response and long-term prognosis. It is suggested that the dysphoric responders, many of whom belong to the category of nuclear or poor prognosis schizophrenia, may be fundamentally different from the others.
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