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  • Title: Chronic intrahepatic cholestasis in sickle cell disease requiring exchange transfusion.
    Author: O'Callaghan A, O'Brien SG, Ninkovic M, Butcher GP, Foster CS, Walters JR, Roberts IA.
    Journal: Gut; 1995 Jul; 37(1):144-7. PubMed ID: 7672666.
    Abstract:
    A 15 year old boy with sickle cell disease developed intrahepatic cholestasis. A course of exchange transfusion successfully corrected the extreme hyperbilirubinaemia over one year. Upon stopping the exchange transfusion programme the hyperbilirubinaemia relapsed but transfusion was effective when reinstituted.
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