These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Investigation of long-term hypocoagulability in rats after intratracheal administration of unfractionated heparin.
    Author: Efimov VS, Rumyantseva AG, Golovlyova OA, Rozkin MYa.
    Journal: Thromb Res; 1993 Feb 01; 69(3):307-13. PubMed ID: 7682732.
    Abstract:
    The comparative study of intratracheal and intravenous administration of heparin on blood coagulation and mast cell population was carried out in experiments in rats. Unlike the intravenous injection of heparin which induces fast short-time inactivation of all clotting factors, single intratracheal injection of heparin inactivated the intrinsic pathway of thrombin generation. Long-term hypocoagulability after intratracheal administration of heparin was related to the accumulation of heparin in mast cell.
    [Abstract] [Full Text] [Related] [New Search]