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  • Title: Clinical evaluation of freeze-dried bone allografts in periodontal osseous defects.
    Author: Mellonig JT, Bowers GM, Bright RW, Lawrence JJ.
    Journal: J Periodontol; 1976 Mar; 47(3):125-31. PubMed ID: 768439.
    Abstract:
    Freeze-dried cortical bone allografts of a fine particle size were implanted into wide three-wall, two-wall, one-wall, combination, and furcation defects. Of the 97 defects treated, 23 manifested complete bone regeneration; 39 showed greater than 50%; and 24, less than 50% osseous repair. Twelve defects failed to demonstrate any bony regeneration, of which nine were furcation involvements. From the preliminary data available, there is strong evidence which indicates that freeze-dried bone allografts have definite potential as grafting material in certain periodontal osseous defects. However, final determination must await the outcome of a larger number of cases and also histologic evidence.
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