These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Expression of the endothelial leukocyte adhesion molecule-1 (ELAM-1) on endothelial cells in experimental gingivitis in humans.
    Author: Nylander K, Danielsen B, Fejerskov O, Dabelsteen E.
    Journal: J Periodontol; 1993 May; 64(5):355-7. PubMed ID: 7685818.
    Abstract:
    In inflammatory conditions, mediators such as interleukin-1 (IL-1) are released by resident tissue cells as well as by infiltrating inflammatory cells. IL-1 activates endothelial cells causing them to express an adhesion molecule called endothelial leukocyte adhesion molecule-1 (ELAM-1). IL-1 is produced by macrophages, but can also be produced by activated keratinocytes. Here we present data from a study of experimentally induced gingivitis, showing the expression of ELAM-1 on endothelial cells even in tissue with little or only minor signs of clinical or histological inflammation. These results indicate that ELAM-1 is found on endothelial cells of the gingiva early in the course of experimental gingivitis, before overt clinical or histological evidence of inflammation is apparent.
    [Abstract] [Full Text] [Related] [New Search]