These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Low-dose intrathecal clonidine releases tachykinins in rat spinal cord.
    Author: Luo L, Wiesenfeld-Hallin Z.
    Journal: Eur J Pharmacol; 1993 Apr 22; 235(1):157-9. PubMed ID: 7686104.
    Abstract:
    In decerebrate, spinalized, unanesthetized rats, 37 pmol (10 ng) intrathecally injected clonidine facilitated the flexor reflex. This effect was blocked by the specific tachykinin antagonists CP-96,345, which acts at the NK1 receptor, and Men 10207, which acts at the NK2 receptor. Thus, low-dose intrathecal clonidine releases the tachykinins substance P and neurokinin A in the spinal cord.
    [Abstract] [Full Text] [Related] [New Search]