These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: HPV-16 E6-E7 differential transcription induced in Siha cervical cancer cell line by interferons.
    Author: De Marco F, Marcante ML.
    Journal: J Biol Regul Homeost Agents; 1993; 7(1):15-21. PubMed ID: 7688490.
    Abstract:
    The transcription of HPV-16 E6/E7 RNA has been studied by the polymerase chain reaction (PCR) in the Siha cervical carcinoma cell line. With this technique, all three different transcripts have been detected: the cDNA colinear E6 form, and the two differentially spliced forms E6*I and E6*II. All types of RNA appear less abundant in cells treated with any of Interferon alpha; beta; or gamma as compared with control cells. Other low abundance cellular RNA remained unaffected. This selective modulation might partially explain the regulation of cell growth potentials displayed by IFN treatment, although other cellular mechanisms besides the one investigated seem to be involved.
    [Abstract] [Full Text] [Related] [New Search]