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  • Title: [Lactate dehydrogenase isoenzymes during early embryonic development in rats].
    Author: Serov OL, Poznakhirkina NA, Korochkin LI.
    Journal: Ontogenez; 1975; 6(2):140-6. PubMed ID: 768856.
    Abstract:
    Using the Coon's immunohistochemical method, antisera against LDH-1 and LDH-5 and electrophoresis in polyacrylamide gel, the polypeptides A and B, i.e. the products of both the LDH genes, were shown to be present both in mature eggs and at the early stages of their development. The spectrum of LDH isozymes in the nature egg is represented, mainly, by LDH-1 and LDH-5. The electrophoretic pattern of the egg LDH depends on the method of extraction since LDH-5 appears to be in the bound form. It has also been shown that the content of LDH-2 and, especially, LDH-3 and LDH-4 in the mature egg is low.
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