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  • Title: [Blood plasma protein fractions in rats during hypokinesia of various durations].
    Author: Gritsuk AI.
    Journal: Aviakosm Ekolog Med; 1993; 27(1):59-64. PubMed ID: 7693127.
    Abstract:
    The studies indicated that the total content of blood plasma protein in the rats decreases on Days 3, 10 and 30 of hypokinesia and returns to norm on Days 70-140. Albumen concentration increases on Day 3, decreases on Day 10 and normalizes during subsequent days of hypokinesia. The level of alpha-1 globulins reduces on Days 3, 10, increases on Days 30, 70 and normalizes on Days 140 of an exposure. Beta-globulin content decreases on Days 3, 10, 70 and 140 of hypokinesia and level of gamma-globulins also reduces on Days 3 and 30 of hypokinesia and exceeds control values on Days 10, 70 and 140 of immobilization. Since metabolism of the main mass of blood plasma proteins is under hormonal control and their synthesis occurs predominantly in the cells of liver and lymphoid system the data obtained are discussed with regard to the peculiarities of hormonal balance and energy metabolism of the immobilized body.
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