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  • Title: External beam radiotherapy for retinoblastoma: I. Whole eye technique.
    Author: Hungerford JL, Toma NM, Plowman PN, Kingston JE.
    Journal: Br J Ophthalmol; 1995 Feb; 79(2):109-11. PubMed ID: 7696227.
    Abstract:
    A retrospective analysis has been performed of the results of external beam radiotherapy for retinoblastoma using a whole eye technique. Local tumour control has been assessed in a consecutive series of 175 eyes in 142 children all of whom received external beam radiotherapy as the primary treatment for retinoblastoma. Follow up ranged from 2 to 17 years (median 9 years). Tumour control rates have been analysed with respect to the Reese Ellsworth classification and the series includes eyes in groups I to V. Focal salvage therapy was given for persistent, recurrent, or new tumours after radiotherapy. Following whole eye radiotherapy alone, the overall ocular cure rate was 57%, though with salvage therapy 80% of eyes could be preserved.
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