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  • Title: Effect of vasoactive intestinal polypeptide on porcine gastrointestinal electrical activity.
    Author: Wechsung E, Houvenaghel A.
    Journal: Peptides; 1994; 15(8):1373-6. PubMed ID: 7700839.
    Abstract:
    The influence of intravenous infusion of VIP, 150 and 300 pmol/kg/min, on gastrointestinal electrical activity was studied in conscious piglets with electrodes implanted in the wall of the antrum pylori, duodenum, jejunum, and ileum. Both doses resulted in a decrease in antral electrical activity. In the small intestine, only the lower dose caused a shortening of the irregular spiking activity phase in the jejunum and ileum. In the jejunum this resulted in a reduction of the MMC interval. It may be concluded that the prevailing effect of VIP is an inhibition of gastrointestinal electrical activity in the piglet.
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