These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: A diterpene from Mikania obtusata active on Trypanosoma cruzi.
    Author: Alves TM, Chaves PP, Santos LM, Nagem TJ, Murta SM, Ceravolo IP, Romanha AJ, Zani CL.
    Journal: Planta Med; 1995 Feb; 61(1):85-7. PubMed ID: 7701002.
    Abstract:
    The diterpene ent-kaur-16-en-19-oic acid (1) was identified as the trypanocidal component of the ethanolic extract from Mikania obtusata D. C. (Asteraceae). This compound presents an IC50 of 0.5 mg/ml (1.66 mM) against the trypomastigote blood form of the Trypanosoma cruzi, the causative agent of Chagas' disease (American trypanosomiasis).
    [Abstract] [Full Text] [Related] [New Search]