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  • Title: N-(indol-3-ylglyoxylyl)amino acid ester derivatives. Synthesis and interaction properties at the benzodiazepine receptor.
    Author: Primofiore G, Da Settimo F, Marini AM, La Motta C, Martini C, Senatore G, Lucacchini A.
    Journal: Farmaco; 1995 Jan; 50(1):5-12. PubMed ID: 7702721.
    Abstract:
    Several N-(indol-3-ylglyoxylyl)alanine and glycine ester derivatives were prepared to evaluate the influence of the ester group size both on affinity and on activity at the benzodiazepine receptor. Moreover, indol-3-ylglyoxylic acid esters, closely related to 3-alkoxy-beta-carbolines, were synthesized and tested in vitro on the benzodiazepine receptor.
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