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  • Title: [Treatment with immunomodulating drugs of patients with operated cancer. Long-term results].
    Author: Sortini A, Di Marco L, Navarra G, Donini A, Fiorentini G, Santini M, Sartori A, Donini I.
    Journal: Minerva Chir; 1994 Nov; 49(11):1101-5. PubMed ID: 7708231.
    Abstract:
    The authors produce a new course of study in order to verify the efficacy of immunomodulatory treatment in cancer-operated patients. In the General Surgical Clinic and Surgical Therapy Institute of University of Ferrara, from July '86 to June '92, 582 cancer-operated patients were treated by immunomodulatory drugs, making use of standard of absolute random. A group (100 patients) was subjected to peroperative anticontagious immunoprophylaxis; B group (482 patients) to postoperative cyclic immunomodulation; in this last group, were codified C group (166 patients) and D group (63 patients), controlled in follow-up, making use of 3 parameters: survival, clinical-oncological restage, performance status. The results obtained confirm the efficacy of the proposed immunomodulatory treatment: a reduction of incidence both early infections and late infections, an increase of survival, falls in clinical-oncological stage to less advanced levels and, above all, an improvement of performance status.
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