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  • Title: Hypokalaemic rhabdomyolysis: an unusual presentation of coeliac disease.
    Author: Williams SG, Davison AG, Glynn MJ.
    Journal: Eur J Gastroenterol Hepatol; 1995 Feb; 7(2):183-4. PubMed ID: 7712311.
    Abstract:
    OBJECTIVE: To describe the clinical presentation and management of a patient with hypokalaemic rhabdomyolysis secondary to coeliac disease. DESIGN: Retrospective study. SETTING: Hospital based. PATIENT: A 60-year-old Caucasian man presenting with weakness caused by hypokalaemic rhabdomyolysis secondary to coeliac disease. INTERVENTIONS: Following the diagnosis by jejunal biopsy, the patient was treated with both intravenous and oral potassium supplements, and a gluten-free diet. OUTCOME MEASURES: Resolution of weakness and restitution of normal villous architecture following treatment. RESULTS: The patient's myopathy responded to the potassium supplements, his diarrhoea and histological changes resolved while on the gluten-free diet. CONCLUSION: Patients with coeliac disease may present with hypokalaemia in association with steatorrhoea. If potassium loss is rapid, rhabdomyolysis may occur. Coeliac disease should be considered a cause of malabsorption-induced hypokalaemic rhabdomyolysis.
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