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  • Title: Early gastric cancer in a patient with Menetrier's disease, lymphocytic gastritis and Helicobacter pylori.
    Author: Johnson MI, Spark JI, Ambrose NS, Wyatt JI.
    Journal: Eur J Gastroenterol Hepatol; 1995 Feb; 7(2):187-90. PubMed ID: 7712313.
    Abstract:
    OBJECTIVE: To describe a patient with early gastric cancer, Menetrier's disease, lymphocytic gastritis and Helicobacter pylori infection. DESIGN: A single patient case report. PATIENT: A 73-year-old man presenting with lower limb deep venous thrombosis was found to have a gastric adenocarcinoma on upper gastrointestinal endoscopy. He subsequently had a total gastrectomy. RESULTS: Histological examination of the resected stomach showed an early gastric cancer and changes typical of Menetrier's disease, lymphocytic gastritis and Helicobacter-associated chronic gastritis. CONCLUSION: This case suggests a link between gastric adenocarcinoma, Menetrier's disease and lymphocytic gastritis. The presence of H. pylori is postulated as a possible aetiology.
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