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  • Title: Amoxicillin/clavulanic acid associated cholestasis in a patient with chronic hepatitis B: a case report.
    Author: Yang WG, Chan CY, Lu CL, Tsay SH, Lee SD.
    Journal: Zhonghua Yi Xue Za Zhi (Taipei); 1995 Jan; 55(1):64-8. PubMed ID: 7712397.
    Abstract:
    We described a patient with history of chronic hepatitis B in whom cholestatic hepatitis occurred after amoxicillin/clavulanic acid (Augmentin) therapy, which to our knowledge is the first case reported in Asia. An atypical serology profile of hepatitis B virus (HBV) markers, demonstrated by negative hepatitis B surface antigen (HBsAg) associated with transient positivity of hepatitis B e antigen (HBeAg) and HBV DNA, was noted during the development of cholestasis.
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