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  • Title: Are infantile myofibromatosis, congenital fibrosarcoma and congenital haemangiopericytoma histogenetically related?
    Author: Variend S, Bax NM, van Gorp J.
    Journal: Histopathology; 1995 Jan; 26(1):57-62. PubMed ID: 7713484.
    Abstract:
    Infantile myofibromatosis, congenital fibrosarcoma and congenital/infantile haemangiopericytoma are generally considered distinct entities. Overlapping microscopic features between infantile myofibromatosis and congenital fibrosarcoma, and between infantile myofibromatosis and congenital/infantile haemangiopericytoma, however, have been noted, but not formally reported. This report concerns six neonatal tumours, each exhibiting more than one of the above patterns, supporting a histogenetic relationship among these entities. Immunohistochemistry for smooth muscle actin was found to be useful in the diagnosis of congenital/infantile haemangiopericytoma, and also served to support a histogenetic relationship with the other two entities under consideration.
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