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  • Title: Diagnostic value of detecting JC virus DNA in cerebrospinal fluid of patients with progressive multifocal leukoencephalopathy.
    Author: Fong IW, Britton CB, Luinstra KE, Toma E, Mahony JB.
    Journal: J Clin Microbiol; 1995 Feb; 33(2):484-6. PubMed ID: 7714213.
    Abstract:
    JC virus DNA was detected by PCR in the cerebrospinal fluid of 17 of 23 (73.9%) patients with confirmed cases of progressive multifocal leukoencephalopathy and 2 of 48 (4.2%) controls without progressive multifocal leukoencephalopathy. The sensitivity and specificity of this PCR were 74 and 95.8%, respectively, while the positive and negative predictive values were 89.5 and 88.5%, respectively.
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