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  • Title: Phobic symptoms as predictors of nonresponse to drug therapy in panic disorder patients (a preliminary report).
    Author: Slaap BR, van Vliet IM, Westenberg HG, den Boer JA.
    Journal: J Affect Disord; 1995 Jan 11; 33(1):31-8. PubMed ID: 7714306.
    Abstract:
    Factors that predict nonresponse to drug therapy (brofaromine or fluvoxamine) were investigated in a sample of 44 panic disorder patients. We used a strict definition of nonresponse to find patients who did not respond at all after 12 weeks of treatment. Using this definition, 15 patients (32.6%) were considered nonresponders. Nonresponders had a higher score on the Blood-Injury subscore of the Fear Questionnaire (FQ) and more often had high scores on several FQ subscores, indicative of comorbid phobic symptoms. These variables were subsequently used to predict nonresponse.
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