These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Identical efficacy of terbutaline multidose dry powder inhaler prior to and after 4 weeks of use by asthmatic patients.
    Author: Stallaert RA.
    Journal: Eur J Clin Pharmacol; 1995; 47(5):407-9. PubMed ID: 7720761.
    Abstract:
    We investigated whether the terbutaline multidose dry powder inhaler (Turbuhaler) has the same efficacy after routine daily use as it has when new. Thirty-three adult asthmatic patients were tested on two occasions. The bronchodilatory effect of inhalations of 0.5, 0.5 and 1.0 mg terbutaline at 40-min intervals from the same device was determined prior to and after using the device at least three times a day for 4 weeks. When tested for the second time, 116-186 doses had been inhaled. Although baseline forced expiratory volume in 1 s (FEV1) was slightly higher after the 4-week treatment period, the bronchodilatory effect of the inhaled terbutaline doses was identical. We conclude that the multidose dry powder inhaler is as effective in delivering terbutaline after a period of routine daily use as it is when new.
    [Abstract] [Full Text] [Related] [New Search]