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  • Title: Lichen planus pemphigoides: identification of 180 kd hemidesmosome antigen.
    Author: Tamada Y, Yokochi K, Nitta Y, Ikeya T, Hara K, Owaribe K.
    Journal: J Am Acad Dermatol; 1995 May; 32(5 Pt 2):883-7. PubMed ID: 7722050.
    Abstract:
    We describe a man with lichen planus pemphigoides. Direct immunofluorescence studies of peribullous skin showed linear deposition of IgG and C3 in the basement membrane zone. Indirect immunofluorescence studies disclosed circulating anti-basement membrane zone antibodies. Immunoelectron microscopy demonstrated binding of antibodies to the hemidesmosomes and lamina lucida. The patient's serum defined only the minor bullous pemphigoid antigen with a molecular weight of 180 kd. These findings suggest the coexistence of lichen planus and bullous pemphigoid in lichen planus pemphigoides.
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