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  • Title: Neutrophilic eccrine hidradenitis: report of two cases.
    Author: Kanzaki H, Oono T, Makino E, Arata J, Oda M, Akazai A.
    Journal: J Dermatol; 1995 Feb; 22(2):137-42. PubMed ID: 7722091.
    Abstract:
    BACKGROUND: Neutrophilic eccrine hidradenitis (NEH) is an uncommon, self-limited dermatosis usually attributed to anti-cancer chemotherapy. It is characterized histologically by necrosis of the eccrine gland and neutrophilic infiltrate. OBSERVATIONS: We saw NEH in a 5-year-old boy with acute lymphoblastic leukemia and a 4-year-old girl with acute monocytic leukemia. NEH developed after the anti-leukemic chemotherapy including high dose cytarabine. The eruption was composed of vesicles, papules, and plaques. CONCLUSIONS: Histological findings were compatible with those described in the literature. NEH in our two patients could be attributed to high doses of cytarabine.
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