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  • Title: The synthesis of S-adenosylmethionine by mutants with defects in S-adenosylmethionine synthetase.
    Author: Hobson AC.
    Journal: Mol Gen Genet; 1976 Feb 27; 144(1):87-95. PubMed ID: 772417.
    Abstract:
    Some metK mutants of Salmonella typhimurium with constitutive methionine biosynthesis have no detectable S-adenosylmethionine (SAM) synthetase, the enzyme which converts methionine to SAM, the postulated corepressor of the methionine pathway. However, these mutants are not auxotrophic for SAM, an essential compound for many reactions.
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