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  • Title: [Blue rubber bleb naevus syndrome. Diagnosis and management apropos of 2 cases].
    Author: Pinlong E, Frydman E, Dieckmann K, Faure N, Rolland JC, Lorette G, Ployet MJ.
    Journal: Ann Otolaryngol Chir Cervicofac; 1994; 111(4):228-31. PubMed ID: 7726481.
    Abstract:
    Blue Rubber Bleb Naevus Syndrome is a rare pathology: 70 cases have been noted since the first description, by Gascoyen, in 1860. It is an acquired disease which usually appears before the age of ten. It is marked by angiomatic cutaneo-digestive tumours combined with chronic anaemia and iron deficiency. Its many and various complications, particularly cataclysmic haemorrhages, car jeopardize the vital prognosis throughout. This little known syndrome is rarely diagnosed at the time of its first manifestations. We recall, from two cases and a review of their literature, the clinical characteristics of the syndrome, its complications and its essentially symptomatic treatment. We therefore suggest an approach to its diagnosis.
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