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  • Title: [Morphological changes in the kidneys in refluxogenic nephropathy in patients with congenital and acquired vesicoureteral reflux].
    Author: Pugachev AG, Kudriavtsev IuV, Dachevskiĭ VA, Chumakov AM.
    Journal: Urol Nefrol (Mosk); 1995; (1):4-5. PubMed ID: 7732631.
    Abstract:
    Current views of foreign investigators on refluxogenic nephropathy rest on the results of pig experiments. The authors studied human material: kidneys of children who died of pyelonephritis caused by vesicoureteral reflux. Electron-microscopic and other morphological examinations of the kidney pelvic wall provided evidence for a distinct difference in relevant morphological structures observed in congenital versus acquired reflux. Congenital vesicoureteral reflux displays a specific morphological picture suggesting congenital refluxogenic nephropathy, whereas acquired reflux produces a typical picture of ascending pyelonephritis.
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