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  • Title: Effect of alcohol consumption versus abstinence on 24-h blood pressure profile in normotensive alcoholic patients.
    Author: Maiorano G, Bartolomucci F, Contursi V, Saracino E, Agostinacchio E.
    Journal: Am J Hypertens; 1995 Jan; 8(1):80-1. PubMed ID: 7734102.
    Abstract:
    The aim of this study was to evaluate 24-h ambulatory blood pressure monitoring in 15 male alcoholic normotensive subjects during alcohol consumption and following an abstinence phase and the effects of alcohol consumption compared with a period of 1 week of abstinence. The average 24-h BP was not different, but the diurnal pattern showed a fall in systolic BP early (06:00 to noon; P < .005) and late (18:00 to 22:00; P < .002) in the day during abstinence. BP variability was increased during the alcohol phase (P < .05). This study showed that 1 week of abstinence does not influence 24-h BP levels in normotensive subjects, but alters the diurnal pattern, characterized by a fall in systolic BP and increased BP variability.
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