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  • Title: Contralateral suppression of transient evoked otoacoustic emissions in guinea-pigs: effects of gentamicin.
    Author: Aran JM, Erre JP, Avan P.
    Journal: Br J Audiol; 1994; 28(4-5):267-71. PubMed ID: 7735155.
    Abstract:
    A single injection of gentamicin in the awake guinea-pig induces a transient blockade of the suppression by contralateral white noise of tone-pip evoked compound action potential (Smith et al., 1994). We report here the reversible blockade, in exactly the same experimental conditions, of the suppression of click-evoked otoacoustic emissions. These observations confirm the transient action of gentamicin at the medial efferent/outer hair cell synapse, likely via the reversible blockade of calcium channels observed in vitro (Dulon et al., 1989).
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