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  • Title: Progress in understanding and treating Parkinson's disease.
    Author: Barbeau A.
    Journal: Can J Neurol Sci; 1976 May; 3(2):81-4. PubMed ID: 773522.
    Abstract:
    This review evaluates the long-term results of Levodopa therapy in Parkinson's disease upon quality of life, prolongation of survival and excess mortality. It also focuses on recent and new therapeutic approaches: Levodopa in combindation with a Dopa-decarboxylase inhibitor or MAO-B inhibitor, dopamine agonists and an active tripeptide: L-prolyl-L-leucylglycine amide (MIF-I). It ends by looking at new avenues of etiological research in Parkinson's disease which may indicate specific accelerated ageing of catecholaminergic (pigmented) neuronal systems.
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