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  • Title: Increased technetium-99m-HMPAO uptake in grade II astrocytoma.
    Author: Grünwald F, Menzel C, Pietsch T, Pavics L, Hufnagel A, Biersack HJ.
    Journal: J Nucl Med; 1995 May; 36(5):804-6. PubMed ID: 7738652.
    Abstract:
    Most brain tumors show decreased uptake of blood flow tracers in brain SPECT imaging and in some cases meningiomas show increased uptake, mainly associated with high regional blood flow values. A reason for regionally increased tracer uptake is partial epilepsy when a tracer is injected during the ictal phase. We present a case of a histologically proven Grade II astrocytoma in the mesial part of the left temporal lobe that caused complex partial seizures. After tracer injection during a phase without signs of clinical seizure, markedly increased uptake of 99mTc-hexamethylpropyleneamine oxime (99mTc-HMPAO) occurred, although the tumor was partially calcified.
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