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  • Title: [Thyroid pathology: evaluation of the average value of NORs and its potential diagnostic and prognostic application].
    Author: Iuele R, Gallippi G, Giacchetto C.
    Journal: Pathologica; 1994 Oct; 86(5):525-7. PubMed ID: 7739878.
    Abstract:
    Argyrophilie technique to identify nucleolar organizer regions (NORs) applied in formalin-fixed paraffin sections of thyroid tissue allow us to reveal NORs as block dots in the nuclei of cells. In the present study the relationship between number of NORs and cellular activation emphasize significant statistical data: it was found that the number of AgNORs in malignant thyroid lesions significantly exceeded those of benign thyroid lesions. This objective assessment associated with easily method show an advantage in thyroid diagnostic histopathology an adjunct to routine methods.
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