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  • Title: [Allogenic bone marrow transplantation in Wiskott-Aldrich syndrome].
    Author: Maldonado MS, Muñoz A, Otheo de Tejada E, Roldán E, Aymerich L, Brieva JA.
    Journal: Med Clin (Barc); 1993 Sep 11; 101(7):258-60. PubMed ID: 7746001.
    Abstract:
    Two males of 3 and 3 1/2 years of age with the Wiskott-Aldrich syndrome who underwent bone marrow transplantation from an HLA compatible brother following conditioning treatment with busulphan and cyclophosphamide are described. In both patients the taking of the graft was proven by study of blood subgroups and correction of the immunodeficiency, normalization of platelet number and function and disappearance of cutaneous eczema were seen. At 3 and 1 year respectively of the transplantation the patients showed no evidence of graft versus host disease and no severe infections or hemorrhagic episodes have seen.
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